Located at 24 E 81st St, New York, Sistina is an upscale Italian restaurant that impresses with its sophisticated ambiance and refined menu. With a stellar 4.3 rating from nearly 500 reviews, it offers exquisite Italian fare, including vegetarian and gluten-free options, complemented by an extensive wine list. Perfect for families and groups, Sistina ensures a memorable dining experience with exceptional service and beautifully decorated interiors. Reservations recommended.