Casa Santo Stefano – Italian
Housed in a beautifully restored 1920s macaroni factory, this Sicilian sanctuary transports guests to a bygone era with its exposed brick walls, vintage family portraits, and a warm, nostalgic glow. The air carries the rich, savory perfume of slow-simmered Sunday gravy and hand-rolled pastas, while the vibrant flavors of the Mediterranean come alive in dishes that celebrate the soulful culinary heritage of the island. Whether dining in the bustling, art-filled hall or enjoying a sunset cocktail on the breezy rooftop, the experience feels like a heartfelt invitation into a grand Sicilian home.
1607, North 22nd Street, Tampa, FL, 33605 +18132481925 https://casasantostefano.com0Cuisine: Italian
Price range: $$$
Dietary options: high-protein, keto, low-carb, vegan, vegetarian, heart-healthy, low-fat, low-sodium, paleo, pescatarian, plant-based, whole30, anti-inflammatory, atkins, dash-sodium-reduced, gerd, high-fiber, low-cholesterol, south-beach, aip, alkaline, carnivore, renal, tlc, volumetrics, zone, juice-cleanse, lectin-free, macrobiotic, slow-carb
Currently closed
Hours
- Monday - Sunday
- 11:00 AM - 10:00 PM
Menu
Antipasti
- Meatballs della Nana - $12: Blend of pork and beef meatballs gently braised in house-made tomato sauce, Pecorino Romano cheese Available at: dinner, lunch
- Grilled Italian Sausage - $15: Grilled Tony Fig's Italian sausage with lemon Dietary tags: Low-Sodium
- Arancini al Burro - $14: Teardrop-shaped fried saffron risotto combined with fresh mozzarella and prosciutto cotto, served with house-made tomato sauce Dietary tags: Low-Sodium
- Fried Calamari - $18: Semolina-dusted fried calamari and zucchini strings with spicy Calabrian pepper tomato sauce Dietary tags: High-Protein, Pescatarian, Low-Sodium, DASH Sodium-Reduced
- Mussels J. Matassini - $20: Twenty fresh Prince Edward Island mussels sautéed with Sicilian olive oil, garlic, crushed red pepper, parsley, grape tomato sauce, served with focaccia Dietary tags: Pescatarian
- Gambino Mediterraneo - $18: Sautéed shrimp in prosecco sauce, garlic and citrus Dietary tags: Pescatarian, Lectin-Free
- Toasted Gnocchi - $14: Toasted fresh gnocchi stuffed with four cheeses, served with house-made tomato sauce Dietary tags: Vegetarian, Pescatarian
- Eggplant Millefoglie - $14: Baked eggplant terrine layered with Pecorino Romano cheese, tomato sauce
- Stuffed Artichokes Reina - $16: Roman artichoke stuffed with Pecorino Romano cheese, lemon juice and Sicilian-style crispy breadcrumbs Dietary tags: Vegetarian, Pescatarian, Low-Sodium, High-Fiber, Juice-Cleanse
- Burrata in Purgatorio - $16: Breaded and fried burrata cheese in spicy tomato sauce with toast points Dietary tags: Vegetarian, Pescatarian, Low-Sodium
Pizza
- Margherita Pizza - $16: Tomato sauce, fresh mozzarella, fresh basil, extra-virgin olive oil Dietary tags: Vegetarian, Pescatarian, Heart-Healthy, Low-Sodium, TLC
- Vegetarian Pizza - $16: Mushrooms, eggplant, spinach, mozzarella, tomato sauce Dietary tags: Vegetarian, Pescatarian, Heart-Healthy, Low-Sodium, Anti-Inflammatory, DASH Sodium-Reduced, GERD-Friendly, Zone, Volumetrics, TLC
- Sicilian Hot Honey Pizza - $18: Soppressata, ricotta, mozzarella, Calabrese cherry pepper, hot honey drizzle
- Pizza Suprema - $20: House-made meatballs, crumbled sausage, mushroom, peppers, onions, mozzarella, tomato sauce
- La Soppressata Pizza - $18: Mozzarella, spicy tomato sauce and thinly-sliced soppressata salami
Salads
- Valenti's Burrata Salad - $16: Burrata cheese, tomato, pickled red onion and arugula salad with balsamic vinaigrette Dietary tags: Vegetarian, Pescatarian
- Caesar Salad - $15: Romaine lettuce, Caesar dressing, garlic croutons, shaved Pecorino Romano Dietary tags: Pescatarian, Anti-Inflammatory
- Caesar Salad with Grilled Chicken - $18: Romaine lettuce, Caesar dressing, garlic croutons, shaved Pecorino Romano, grilled chicken
- Pizza Parlor Giant Italian Salad - $16: Lettuce, celery, grape tomato, prosciutto cotto, provolone, Sicilian olives, Italian vinaigrette, parmesan
Pasta
- Pasta Bolognese - $18: Spaghetti or casarecce with pork and beef bolognese, plum tomatoes, garlic, celery, carrots, tomato sauce, Pecorino Romano
- Spaghetti Nana Maria - $20: Meatball, pork shoulder, Italian sausage, hard-boiled egg, tomato sauce, Pecorino Romano Dietary tags: High-Protein
- Spaghetti with Meatballs - $20: Beef and pork meatballs braised in rich sauce, Pecorino Romano Dietary tags: Low-Sodium, Anti-Inflammatory, DASH Sodium-Reduced, TLC
- Casarecce Rinaldi - $22: Casarecce pasta, sautéed crumbled sausage, peas, garlic, crushed red pepper, light cream sauce Dietary tags: High-Fiber
- Lasagna - $20: Fresh pasta, garlic ricotta, mozzarella, Pecorino Romano, Italian sausage, Bolognese meat, tomato sauce Dietary tags: Low-Sodium, Anti-Inflammatory, DASH Sodium-Reduced, TLC
- Linguine with Clams - $28: Littleneck clams, garlic, crushed red pepper, parsley, white wine tomato sauce, butter, Sicilian olive oil Dietary tags: Pescatarian
- Linguine with Shrimp Felicione - $22: Shrimp, white wine, grape tomato sauce, shallots, garlic, spicy crushed red pepper Dietary tags: Pescatarian
- Linguine Frutti di Mare - $40: Lobster, littleneck clams, mussels, squid, shrimp, garlic, white wine, spicy red sauce Dietary tags: Pescatarian
- Pasta alla Norma - $20: Casarecce maccheroni, fried eggplant, house-made tomato sauce, garlic, grated ricotta salata cheese Dietary tags: Vegetarian, Pescatarian
- Ricotta Ravioli - $22: Ravioli stuffed with ricotta and pesto, tomato sauce, Pecorino Romano Dietary tags: Vegetarian, Pescatarian, Heart-Healthy, Low-Sodium, Anti-Inflammatory, DASH Sodium-Reduced, TLC
- Vegetable Gnocchi - $22: Potato gnocchi, cremini mushrooms, broccolini, baby spinach, peas, garlic, shallots, light cream sauce, Pecorino Romano Dietary tags: Vegetarian, Pescatarian, High-Fiber
Main Courses
- Chicken Marsala - $25: Boneless chicken breasts scaloppine, Marsala wine, garlic, cremini mushrooms, sautéed baby potatoes Dietary tags: High-Protein, Atkins, Slow-Carb
- Chicken Parmigiana Scaglione - $22: Boneless chicken breasts, tomato sauce, mozzarella, Parmesan, basil, served with maccheroni pasta pomodoro
- Grilled Pork Chop - $20: 8 oz. Compart Duroc pork chop, fruit mostarda, vincotto balsamic reduction, sautéed baby potatoes Dietary tags: Whole30, Paleo
- Veal Scaloppine Milanesa - $28: Breaded veal slice, grilled and topped with tomato, onion, and green pepper sauce, served with baby potatoes Dietary tags: Low-Sodium, DASH Sodium-Reduced
- Veal Scaloppine Marsala - $28: Pan-fried veal scaloppine, Marsala sauce, cremini mushrooms, baby potatoes, broccolini
- Merluzzo with Sicilian Pesto - $32: Wild-caught merluzzo fish, house-made pesto Siciliano, served with Aglio e Olio pasta and spinach Dietary tags: Pescatarian
- Grilled Sea Bass - $38: Chargrilled Mediterranean sea bass, olive oil, herbs, served with broccolini and grilled lemon Dietary tags: Keto, Low-Carb, Whole30, Pescatarian, Paleo, Low-Sodium, Atkins, South-Beach, Carnivore, Alkaline, AIP, Renal, Macrobiotic, Slow-Carb, Lectin-Free
- Grouper al Limone - $38: Fresh Gulf grouper, lemon butter sauce, capers, white wine, served with broccolini Dietary tags: Pescatarian
- Swordfish Messina - $28: Swordfish fillet, tomatoes, onions, capers, olives, served with broccolini Dietary tags: High-Protein, Whole30, Pescatarian, Paleo, Anti-Inflammatory, South-Beach, Low-Cholesterol, Alkaline, Slow-Carb
Sandwiches
- Panino Siciliano - $16: Prosciutto, mortadella, ham, sopressata, provolone, tomato, Calabrian peppers, olives, vinaigrette on muffaletta bread, served with chips
- Chicken Parmigiana Sandwich - $18: Chicken breast, garlic, tomato sauce, mozzarella on Cuban bread, served with chips Dietary tags: High-Protein, Low-Sodium, DASH Sodium-Reduced
- Casa's Italian Steak Sandwich - $18: Shaved rib-eye, green peppers, onions, romaine, tomatoes, lemon vinaigrette on Cuban bread, served with chips Dietary tags: High-Protein, Low-Sodium, DASH Sodium-Reduced
- Cartocciata Meatballs - $16: Sicilian handheld calzone stuffed with meatballs, tomato sauce, Pecorino Romano, basil, served with chips
Sides
- Broccolini - $9: Sautéed in olive oil, garlic, red pepper Dietary tags: High-Protein, Keto, Low-Carb, Vegan, Vegetarian, Whole30, Pescatarian, Paleo, Heart-Healthy, Plant-Based, Low-Sodium, Low-Fat, Anti-Inflammatory, Atkins, South-Beach, DASH Sodium-Reduced, Low-Cholesterol, GERD-Friendly, Zone, Volumetrics, TLC, Alkaline, Renal, Slow-Carb
- Maccheroni al Pomodoro - $7: Sicilian casarecce with tomato sauce and Pecorino Romano Dietary tags: Vegetarian, Pescatarian
- Sautéed Potatoes - $7: Baby Yukon Gold potatoes with Sicilian herbs and garlic Dietary tags: Vegan, Vegetarian, Whole30, Pescatarian, Paleo, Heart-Healthy, Plant-Based, Low-Sodium, Anti-Inflammatory, DASH Sodium-Reduced, Low-Cholesterol, TLC, Alkaline
- Sautéed Spinach - $9: Fresh spinach, olive oil, garlic Dietary tags: Vegan, Vegetarian, Whole30, Pescatarian, Paleo, Heart-Healthy, Plant-Based, Low-Sodium, Low-Fat, Anti-Inflammatory, DASH Sodium-Reduced, Low-Cholesterol, GERD-Friendly, Volumetrics, TLC, Alkaline, AIP, Macrobiotic, Lectin-Free
- Caponata - $8: Eggplant, garlic, celery, tomatoes, olives, capers, pine nuts, raisins, red onions Dietary tags: Vegan, Vegetarian, Whole30, Pescatarian, Paleo, Plant-Based, Alkaline
Desserts
- Ricotta Cannoli - $12: Sicilian ricotta, chocolate chips, candied citrus, pistachio Dietary tags: Vegetarian, Pescatarian, Low-Sodium, High-Fiber
- Tiramisù - $12: Coffee-dipped ladyfingers, rum, mascarpone cream, dark cocoa Dietary tags: Vegetarian, Pescatarian, Low-Sodium
- Lemon Cake - $12: Vanilla cake, lemon mascarpone, limoncello syrup Dietary tags: Vegetarian, Pescatarian, Low-Sodium, TLC
- Affogato al Caffe - $10: Stracciatella gelato, espresso, whipped cream, Frangelico, almonds, chocolate chips Dietary tags: Vegetarian, Pescatarian, Low-Sodium
- Gelato - $9: Assorted flavors: dark chocolate, vanilla, pistachio, stracciatella Dietary tags: Heart-Healthy, Low-Sodium, TLC
Beverages
- Espresso - $3
- Cappuccino - $5
- Limonata Cocktail - $12: Strega liqueur, limoncello, rosemary syrup Dietary tags: Vegan, Vegetarian, Pescatarian
- Sicilian Aperol Spritz - $12: Tito's vodka, sparkling wine, limoncello, Aperol Dietary tags: Vegan, Vegetarian, Pescatarian, Plant-Based, Lectin-Free
- Blueberry Lemon Spritz Mocktail - $7: Sicilian lemonade, muddled blueberries Dietary tags: Vegan, Vegetarian, Pescatarian
Restaurants near Casa Santo Stefano
- Bernini — Italian
- La Terrazza Restaurant — Italian
- Due Amici — Italian
- Mangia Bene Pizzeria — Italian
- Tampa Pizza Company — Italian
- CONCESSIONS - TERRACE-326 PAPA JOHN’S PIZZA — Italian
- Oggi Itailian — Italian
- Osteria Bar and Kitchen — Italian
- Eddie & Sam's — Italian
- Donatello — Italian
- WINE AND WOOD — Italian
- Islands Pizza Tavern — Italian
